Health Innovations via Engineering (HIVE) is a community of expert health engineers bound in a virtual core by their vision to address the grand challenges of medicine by engineering technological solutions.

HIVE aims to bring together engineers from across UCSF departments and schools—Dentistry, Medicine, Nursing and Pharmacy—to develop and apply engineering approaches to improve human health. This initiative builds on the talent of engineering-based faculty across the institution by providing opportunities to connect, collaborate, and address unsolved challenges at the intersection of engineering and health.

 

 

Community of Engineers

Tejal Desai, PhD

Professor
Bioengineering

Tejal Desai is a professor at the Department of Bioengineering and Therapeutic Sciences within the Schools of Pharmacy and Medicine at the University of California, San Francisco (UCSF); the director of the NIH training grant for the Joint Graduate Program in Bioengineering at the University of California, Berkeley (UCB) and UCSF; and the founding director of the UCSF/UC Berkeley Master’s Program in Translational Medicine.

Tamara Alliston, PhD

Professor
Orthopaedic Surgery

Dr. Tamara Alliston is a Professor in the Department of Orthopaedic Surgery and is co-Director of the Skeletal Biology Core of the Center of Musculoskeletal Biology and Medicine. Her research focuses on the mechanobiologic pathways controlling stem cell and skeletal cell differentiation in bone and cartilage, seeking to understand how these pathways maintain the mechanical integrity of the healthy skeleton, and how this is disrupted in skeletal diseases like arthritis and osteoporosis. In particular, she studies the mechanobiology of TGFß in the skeleton.

Mekhail Anwar, MD, PhD

Assistant Professor
Radiation Oncology

Mekhail Anwar, M.D., Ph.D., is an Assistant Professor in the Department of Radiation Oncology at the University of California, San Francisco, with expertise in electrical engineering focusing on integrated circuits and micro-fabricated sensors for cancer imaging with a clinical practice in Radiation Oncology specializing in the multimodality treatment of malignancies using focal, targeted radiation therapy.

Edward Chang, MD

Professor
Neurological Surgery

Dr. Edward Chang is Professor of Neurological Surgery and co-Director of the Center for Neural Engineering at UC Berkeley and San Francisco. Dr. Chang’s clinical expertise is surgical therapies for intractable epilepsy, trigeminal neuralgia, pain, hemifacial spasm, and adult brain tumors.

Zev Gartner, PhD

Professor
Pharmaceutical Chemistry

Dr. Zev Gartner is a Professor in the Department of Pharmaceutical Chemistry and is co-Director of the UCSF-based, multi-institution Center for Cellular Construction. He graduated from UC Berkeley and earned his PhD in Chemistry from Harvard University in 2004. He is working to understand how cells assemble into multicellular tissues; how the structure of tissues coordinate the behavior of individual cells; and how changes to tissue structure drive the progression of diseases like cancer. Toward these goals, he and his lab build, perturb, and model human tissues in vitro using techniques from the chemical, engineering, physical and biological sciences.

Sunita Ho, MS, PhD

Professor
Preventive & Restorative Dental Sciences

Dr. Sunita Ho is a bioengineer who focuses on studies related to biomineralization, biomechanics, and biomaterials. She is a Professor in the Department of Urology, School of Medicine, and in the Department of Preventive and Restorative Dental Sciences (PRDS), School of Dentistry. Dr. Ho focuses on site-specific interventions to mitigate the beginnings of pathologic formations of biomaterials in humans. She investigates the regenerative aspects of soft and hard tissue attachments within craniofacial and musculoskeletal joints. Using biomechanics and mechanobiological approaches, Dr. Ho maps the special and temporal aspects of “mechano-responsiveness.”

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Matthew Kutys, PhD

Assistant Professor
Cell and Tissue Biology

The Kutys Lab spans disciplinary boundaries between cell biology and engineering to investigate tissue morphogenic processes associated with human development, regeneration and disease. Ultimately, we are interested in uncovering fundamental molecular and mechanical mechanisms that conspire across time and length scales to organize and shape human tissues.

Jeffrey Lotz, PhD

Professor
Orthopaedic Surgery

Dr. Jeffrey Lotz, Ph.D., holds the David S. Bradford, MD, Endowed Chair in Orthopaedic Surgery and vice chair for research. He has earned several awards for spine research, and serves as a deputy editor for the journal, Spine. Dr. Lotz is the founding director of the UCSF Core Center for Musculoskeletal Biology in Medicine and the NSF Center for Disruptive Musculoskeletal Innovations, and corresponding PI for the newly established Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration (C-DOCTOR). He has expertise in spine biomechanics, intervertebral disc biology, and tissue engineering.

Shuvo Roy, PhD

Professor
Bioengineering

Dr. Shuvo Roy is a UCSF bioengineer working on the world’s first implantable bio-artificial kidney. His focus is on medical device development to address unmet clinical needs by leveraging his background in microelectromechanical systems (MEMS) along with advances in biomaterials, electronics, and nanotechnology to advance health worldwide. He is a professor in the Department of Bioengineering and Therapeutic Sciences and the Director of the Biodesign Laboratory, along with an adjunct appointment in the Department of Surgery. In addition, Dr. Roy serves as the Technical Director of The Kidney Project and is a founding member of the FDA-supported UCSF-Stanford Pediatric Device Consortium. 

Seth Shipman, PhD

Assistant Professor
Bioengineering

Dr. Seth Shipman's research focuses on cellular systems in the midst of change. His lab seeks to better understand how the order of transcriptional events during development can drive changes in cell fate, and to better intervene in diseases characterized by change, like progressive neurodegeneration and cancer. His lab takes a molecular engineering approach, leveraging the versatility of DNA as a programmable biological polymer to gather data without destroying cells, and deliver therapeutics that can modify their effect based on cell context.

Valerie Weaver, PhD

Professor
Surgery

Dr. Weaver is a professor in the Department of Surgery and the director of the Center for Bioengineering and Tissue Regeneration. Her research focuses on the contribution of force, cell-intrinsic as well as extracellular matrix, to oncogenesis and tumor development. Dr. Weaver and her lab employ 2- and 3-D in-vitro cell culture techniques, clinical samples and animal models with force application techniques, traction force and atomic force microscopy to assess the influence of the mechanical aspects of the cell environment on cell behavior and tumor progression.

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Catera Wilder, PhD

Assistant Professor
Bioengineering

Catera Wilder, Ph.D. is an Assistant Professor in the Department of Bioengineering and Therapeutic Sciences at the University of California San Francisco and Chan Zuckerberg Biohub Investigator. She received her Ph.D. in Biomedical Engineering at Georgia Institute of Technology and Emory University (2016) under the direction of Manu Platt. As a UCLA Chancellor’s Postdoctoral Fellow in the lab of Alexander Hoffmann (2016-2022) she focused on understanding innate immune and inflammatory responses by studying ISGF3 transcription factor dynamic regulation using a systems biology approach.

 

Affiliates

Reza Abbasi Asl, PhD

Assistant Professor
Neurology

The Abbasi Lab develops interpretable models and algorithms based on machine learning principles to understand functions of the brain and related disorders. To discover and model the functions of neurons, the lab studies applications of machine learning in the analysis of large-scale multi-modal datasets including electrophysiology, calcium imaging, electron microscopy, and spatial gene expression profiles.

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Peng Cong, PhD

Adjunct Professor
Neurological Surgery

Dr. Cong is currently Margaret Liu Collins and Edward B. Collins Professor and Director of Brain Interface Technology, Department of Neurological Surgery at University of California San Francisco (UCSF). His work is aimed at translational brain computer interface (BCI) and implantable neuromodulation technologies to address complex neurological disorders, including depression, ALS, and impacts of stroke.

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Jeremy Gordon, PhD

Assistant Adjunct Professor
Radiology

Dr. Jeremy Gordon earned a PhD in Medical Physics from the University of Wisconsin. He was a postdoctoral scholar at UCSF (2013-2016), followed by a role as senior development engineer (2016-2020) in the UCSF Department of Radiology and Biomedical Imaging.

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Vasilis Ntranos, PhD

Asst Professor In Residence
Diabetes Center

Vasilis Ntranos obtained his PhD in Electrical Engineering from USC in 2015, working on network information theory problems and their applications in data storage and wireless communications. After his graduate studies, Vasilis moved his focus to computational biology and machine learning, completing his postdoctoral training in EECS and Biological Engineering, working with Lior Pachter and David Tse at UC Berkeley, Stanford, and Caltech.