Professor
Neurological Surgery
+1 415 502-7346
Dr. Edward Chang is Professor of Neurological Surgery and co-Director of the Center for Neural Engineering at UC Berkeley and San Francisco. Dr. Chang’s clinical expertise is surgical therapies for intractable epilepsy, trigeminal neuralgia, pain, hemifacial spasm, and adult brain tumors. He specializes in advanced neurophysiologic brain mapping methods, including awake speech and motor mapping, to safely perform neurosurgical procedures in eloquent areas of the brain. Dr. Chang was awarded the 2015 Blavatnik National Laureate in Life Sciences and is a Bowes Biomedical Investigator in 2018.
Publications
3D spatial sampling to quantify morphologic heterogeneity in isocitrate dehydrogenase-wildtype glioblastoma.
Journal of neuropathology and experimental neurology
Modified far lateral approach for a 4th ventricular tumor with CPA extension: Illustrative teaching case.
World neurosurgery
Experience and safety of intraoperative Neuropixels: a case series of 56 patients.
Journal of neurosurgery
Towards individualized deep brain stimulation: A stereoencephalography-based workflow for unbiased neurostimulation target identification.
bioRxiv : the preprint server for biology
Implications of shared motor and perceptual activations on the sensorimotor cortex for neuroprosthetic decoding.
Journal of neural engineering
Management of glioma-associated epilepsy in the molecular era: a review of the literature and an institutional experience.
Neurosurgical focus
The development of aperiodic neural activity in the human brain.
Nature human behaviour
Correlation between time to postoperative seizure onset and time to tumor progression in a cohort of adult-type diffuse gliomas with molecular characterization.
Journal of neurosurgery
Speech sequencing in the human precentral gyrus.
Nature human behaviour
Challenges and opportunities for advancing functional MRI in clinical practice.
Brain : a journal of neurology
Role for Left Dorsomedial Prefrontal Cortex in Self-Generated, but not Externally Cued, Language Production.
Neurobiology of language (Cambridge, Mass.)
Systematic Review and Meta-Analysis of Bilateral Centromedian Nucleus Neuromodulation for Multifocal and Generalized Epilepsy.
Neuromodulation : journal of the International Neuromodulation Society
Outcome comparison between interposition and "contactless" transposition microvascular decompression approaches for trigeminal neuralgia.
Journal of neurosurgery
Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation.
bioRxiv : the preprint server for biology
Trends in Thalamic Stereoelectroencephalography Utilization During Phase II Monitoring in North America: A Survey.
Operative neurosurgery (Hagerstown, Md.)
Dynamics of auditory word form encoding in human speech cortex.
bioRxiv : the preprint server for biology
Implications of shared motor and perceptual activations on the sensorimotor cortex for neuroprosthetic decoding.
medRxiv : the preprint server for health sciences
An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes.
bioRxiv : the preprint server for biology
The development of aperiodic neural activity in the human brain.
bioRxiv : the preprint server for biology
Rapid resolution of depression and epilepsy following resection of a septal region tumor: illustrative case.
Journal of neurosurgery. Case lessons
Distributed intracranial activity underlying human decision-making behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience
A streaming brain-to-voice neuroprosthesis to restore naturalistic communication.
Nature neuroscience
Invasive Brain Mapping Identifies Personalized Therapeutic Neuromodulation Targets for Obsessive-Compulsive Disorder.
medRxiv : the preprint server for health sciences
Anatomical and behavioural correlates of auditory perception in developmental dyslexia.
Brain : a journal of neurology
DREDge: robust motion correction for high-density extracellular recordings across species.
Nature methods
Influences of electrode density on intracranial seizure localisation: a single-blinded randomised crossover study.
EBioMedicine
Inhibitory control of speech production in the human premotor frontal cortex.
Nature human behaviour
Reinstatement and transformation of memory traces for recognition.
Science advances
Longitudinal profiling of IDH-mutant astrocytomas reveals acquired RAS-MAPK pathway mutations associated with inferior survival.
Neuro-oncology advances
Stimulation-based compassion mapping to assess risk of insular resection for surgical epilepsy management: illustrative case.
Journal of neurosurgery. Case lessons
Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices.
Nature neuroscience
Brain-Computer Interfaces for Restoring Communication.
The New England journal of medicine
Anatomical and behavioral correlates of auditory perception in developmental dyslexia.
bioRxiv : the preprint server for biology
Surgical outcomes following resection in patients with language dominant posterior quadrant epilepsy.
Epilepsy & behavior reports
Hippocampal network activity forecasts epileptic seizures.
Nature medicine
Author Correction: A high-performance neuroprosthesis for speech decoding and avatar control.
Nature
A bilingual speech neuroprosthesis driven by cortical articulatory representations shared between languages.
Nature biomedical engineering
The speech neuroprosthesis.
Nature reviews. Neuroscience
Stereoelectroencephalography Electrode Implantation for Inpatient Workup of Treatment-Resistant Depression.
Neurosurgery
Development and validation of a nonverbal consensus-based semantic memory paradigm in patients with epilepsy.
Journal of the International Neuropsychological Society : JINS
Quantitative assessment of preanalytic variables on clinical evaluation of PI3/AKT/mTOR signaling activity in diffuse glioma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Parallel Encoding of Speech in Human Frontal and Temporal Lobes.
bioRxiv : the preprint server for biology
Human Anterior Insular Cortex Encodes Multiple Electrophysiological Representations of Anxiety-Related Behaviors.
bioRxiv : the preprint server for biology
Microvascular decompression of a vertebral artery loop causing cervical radiculopathy: illustrative case.
Journal of neurosurgery. Case lessons
Encoding of melody in the human auditory cortex.
Science advances
Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy.
Science advances
Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods.
Journal of neuroscience methods
Intraoperative cortical stimulation mapping with laryngeal electromyography for the localization of human laryngeal motor cortex.
Journal of neurosurgery
"De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
Acta neuropathologica
Dissecting neural computations in the human auditory pathway using deep neural networks for speech.
Nature neuroscience
Neural control of lexical tone production in human laryngeal motor cortex.
Nature communications
DREDge: robust motion correction for high-density extracellular recordings across species.
bioRxiv : the preprint server for biology
Encoding of melody in the human auditory cortex.
bioRxiv : the preprint server for biology
Recommendations for promoting user agency in the design of speech neuroprostheses.
Frontiers in human neuroscience
Ictal EEG Source Imaging With Supplemental Electrodes.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
A Transcriptomic Comparative Study of Cranial Vasculature.
Translational stroke research
Flexible regulation of representations on a drifting manifold enables long-term stable complex neuroprosthetic control.
bioRxiv : the preprint server for biology
Association of CDKN2A alterations with increased postoperative seizure risk after resection of brain metastases.
Neurosurgical focus
Genomic alterations associated with rapid progression of brain metastases.
Neurosurgical focus
Genomic alterations associated with postoperative nodular leptomeningeal disease after resection of brain metastases.
Journal of neurosurgery
Awake Craniotomy and Electrocorticography-Guided Extended Lesionectomy of Motor Cortex Cavernoma: 2-Dimensional Operative Video.
Operative neurosurgery (Hagerstown, Md.)
Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder.
Journal of visualized experiments : JoVE
Latent neural dynamics encode temporal context in speech.
Hearing research
Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans.
Brain stimulation
Closed-loop neurostimulation for the treatment of psychiatric disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
First-in-human prediction of chronic pain state using intracranial neural biomarkers.
Nature neuroscience
Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods.
bioRxiv : the preprint server for biology
Grasp-specific high-frequency broadband mirror neuron activity during reach-and-grasp movements in humans.
Cerebral cortex (New York, N.Y. : 1991)
Phase alignment of low-frequency neural activity to the amplitude envelope of speech reflects evoked responses to acoustic edges, not oscillatory entrainment.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Apraxia of speech with phonological alexia and agraphia following resection of the left middle precentral gyrus: illustrative case.
Journal of neurosurgery. Case lessons
Epileptiform discharges triggered with direct electrical stimulation for treatment-resistant depression: Factors that modulate risk and treatment considerations.
Brain stimulation
Changes in intracranial neurophysiology associated with acute COVID-19 infection.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
CDKN2A/B co-deletion is associated with increased risk of local and distant intracranial recurrence after surgical resection of brain metastases.
Neuro-oncology advances
Identification of risk factors associated with leptomeningeal disease after resection of brain metastases.
Journal of neurosurgery
Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Intact speech perception after resection of dominant hemisphere primary auditory cortex for the treatment of medically refractory epilepsy: illustrative case.
Journal of neurosurgery. Case lessons
Somatic Variants in SVIL in Cerebral Aneurysms.
Neurology. Genetics
A Neurosurgical Functional Dissection of the Middle Precentral Gyrus during Speech Production.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Generalizable spelling using a speech neuroprosthesis in an individual with severe limb and vocal paralysis.
Nature communications
Evaluating syntactic comprehension during awake intraoperative cortical stimulation mapping.
Journal of neurosurgery
Publisher Correction: State-dependent responses to intracranial brain stimulation in a patient with depression.
Nature medicine
Impact of the COVID-19 Pandemic on Neurosurgical Transfers: A Single Tertiary Center Study.
World neurosurgery
Dissociation of Broca's area from Broca's aphasia in patients undergoing neurosurgical resections.
Journal of neurosurgery
Modern intracranial electroencephalography for epilepsy localization with combined subdural grid and depth electrodes with low and improved hemorrhagic complication rates.
Journal of neurosurgery
Involvement of White Matter Language Tracts in Glioma: Clinical Implications, Operative Management, and Functional Recovery After Injury.
Frontiers in neuroscience
Factors associated with preoperative and postoperative seizures in patients undergoing resection of brain metastases.
Journal of neurosurgery
Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy.
Brain communications
Harnessing the Power of Artificial Intelligence in Otolaryngology and the Communication Sciences.
Journal of the Association for Research in Otolaryngology : JARO
Xenotransplantation of porcine progenitor cells in an epileptic California sea lion (Zalophus californianus): illustrative case.
Journal of neurosurgery. Case lessons
Decoding naturalistic affective behaviour from spectro-spatial features in multiday human iEEG.
Nature human behaviour
A single-cell atlas of the normal and malformed human brain vasculature.
Science (New York, N.Y.)
A 680,000-person megastudy of nudges to encourage vaccination in pharmacies.
Proceedings of the National Academy of Sciences of the United States of America
Postsurgical seizure outcome in temporal lobe epilepsy patients with normal or subtle, nonspecific MRI findings.
Journal of neurosurgery
Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain.
Frontiers in neuroscience
Human intracranial recordings reveal distinct cortical activity patterns during invasive and non-invasive vagus nerve stimulation.
Scientific reports
Functional alterations in cortical processing of speech in glioma-infiltrated cortex.
Proceedings of the National Academy of Sciences of the United States of America
Distributed Subnetworks of Depression Defined by Direct Intracranial Neurophysiology.
Frontiers in human neuroscience
Prefrontal Physiomarkers of Anxiety and Depression in Parkinson's Disease.
Frontiers in neuroscience
Speech Computations of the Human Superior Temporal Gyrus.
Annual review of psychology
Decoding Speech from Cortical Surface Electrical Activity. Reply.
The New England journal of medicine
Facial pain and sensory outcomes following resection of tumors compressing the trigeminal nerve.
Journal of neurosurgery
Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.
Frontiers in human neuroscience
Understanding Variable Motor Responses to Direct Electrical Stimulation of the Human Motor Cortex During Brain Surgery.
Frontiers in surgery
Learning nonnative speech sounds changes local encoding in the adult human cortex.
Proceedings of the National Academy of Sciences of the United States of America
Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study.
Brain : a journal of neurology
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy.
Science translational medicine
Thin-film microfabrication and intraoperative testing of µECoG and iEEG depth arrays for sense and stimulation.
Journal of neural engineering
Correlation of natural language assessment results with health-related quality of life in adult glioma patients.
Journal of neurosurgery
Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria.
The New England journal of medicine
Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.
Frontiers in human neuroscience
Effects of anterior thalamic nuclei stimulation on hippocampal activity: Chronic recording in a patient with drug-resistant focal epilepsy.
Epilepsy & behavior reports
Bidirectional propagation of low frequency oscillations over the human hippocampal surface.
Nature communications
Musical Hallucinations in Chronic Pain: The Anterior Cingulate Cortex Regulates Internally Generated Percepts.
Frontiers in neurology
Are preoperative chlorhexidine gluconate showers associated with a reduction in surgical site infection following craniotomy? A retrospective cohort analysis of 3126 surgical procedures.
Journal of neurosurgery
Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.
Frontiers in human neuroscience
Development and Assessment of a Video-Based Intervention to Improve Rhinoplasty Informed Consent.
Facial plastic surgery : FPS
Adaptive tracking of human ECoG network dynamics.
Journal of neural engineering
Human cortical encoding of pitch in tonal and non-tonal languages.
Nature communications
Evidence of state-dependence in the effectiveness of responsive neurostimulation for seizure modulation.
Brain stimulation
State-dependent responses to intracranial brain stimulation in a patient with depression.
Nature medicine
Operative Technique and Lessons Learned From Surgical Implantation of the NeuroPace Responsive Neurostimulation® System in 57 Consecutive Patients.
Operative neurosurgery (Hagerstown, Md.)
Data-Driven, Visual Framework for the Characterization of Aphasias Across Stroke, Post-resective, and Neurodegenerative Disorders Over Time.
Frontiers in neurology
Brain2Char: a deep architecture for decoding text from brain recordings.
Journal of neural engineering
Human Responses to Visually Evoked Threat.
Current biology : CB
Objective score from initial interview identifies patients with probable dissociative seizures.
Epilepsy & behavior : E&B
Long-term pain outcomes in elderly patients with trigeminal neuralgia: comparison of first-time microvascular decompression and stereotactic radiosurgery.
Neurosurgical focus
A Deep Brain Stimulation Trial Period for Treating Chronic Pain.
Journal of clinical medicine
Plug-and-play control of a brain-computer interface through neural map stabilization.
Nature biotechnology
Comparison of Stereotactic Radiosurgery and Radiofrequency Ablation for Trigeminal Neuralgia in Multiple Sclerosis Patients.
Stereotactic and functional neurosurgery
Cortical Encoding of Manual Articulatory and Linguistic Features in American Sign Language.
Current biology : CB
Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor.
Acta neuropathologica communications
Real-world experience with direct brain-responsive neurostimulation for focal onset seizures.
Epilepsia
A Safe Transitions Pathway for post-craniotomy neurological surgery patients: high-value care that bypasses the intensive care unit.
Journal of neurosurgery
Machine translation of cortical activity to text with an encoder-decoder framework.
Nature neuroscience
Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features.
Acta neuropathologica
Interictal Epileptiform Discharges and the Quality of Human Intracranial Neurophysiology Data.
Frontiers in human neuroscience
HDMF: Hierarchical Data Modeling Framework for Modern Science Data Standards.
Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data
Cost-Effectiveness of Advanced Imaging Technologies in the Presurgical Workup of Epilepsy.
Epilepsy currents
A Modular Approach to Vocal Learning: Disentangling the Diversity of a Complex Behavioral Trait.
Neuron
Deep learning as a tool for neural data analysis: Speech classification and cross-frequency coupling in human sensorimotor cortex.
PLoS computational biology
Inhibition of Manual Movements at Speech Arrest Sites in the Posterior Inferior Frontal Lobe.
Neurosurgery
Dynamic network modeling and dimensionality reduction for human ECoG activity.
Journal of neural engineering
Pilot Study of An Intracranial Electroencephalography Biomarker of Depressive Symptoms in Epilepsy.
The Journal of neuropsychiatry and clinical neurosciences
Real-time decoding of question-and-answer speech dialogue using human cortical activity.
Nature communications
A historical cohort of temporal lobe surgery for medically refractory epilepsy: a systematic review and meta-analysis to guide future nonrandomized controlled trial studies.
Journal of neurosurgery
Immature excitatory neurons develop during adolescence in the human amygdala.
Nature communications
Speaker-normalized sound representations in the human auditory cortex.
Nature communications
Biases in processing of mood-congruent facial expressions in depression.
Psychiatry research
Does Adult Neurogenesis Persist in the Human Hippocampus?
Cell stem cell
Critical Language Areas Show Increased Functional Connectivity in Human Cortex.
Cerebral cortex (New York, N.Y. : 1991)
Neural Encoding of Auditory Features during Music Perception and Imagery.
Cerebral cortex (New York, N.Y. : 1991)
Direct Electrical Stimulation of Lateral Orbitofrontal Cortex Acutely Improves Mood in Individuals with Symptoms of Depression.
Current biology : CB
Long-term pain outcomes for recurrent idiopathic trigeminal neuralgia after stereotactic radiosurgery: a prospective comparison of first-time microvascular decompression and repeat stereotactic radiosurgery.
Journal of neurosurgery
Subcellular organization of UBE3A in human cerebral cortex.
Molecular autism
Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex.
eNeuro
Spontaneous Neural Activity in the Superior Temporal Gyrus Recapitulates Tuning for Speech Features.
Frontiers in human neuroscience
Encoding of Multiple Reward-Related Computations in Transient and Sustained High-Frequency Activity in Human OFC.
Current biology : CB
Mood variations decoded from multi-site intracranial human brain activity.
Nature biotechnology
A valid alternative for in-person language assessments in brain tumor patients: feasibility and validity measures of the new TeleLanguage test.
Neuro-oncology practice
Neurosurgical Patients as Human Research Subjects: Ethical Considerations in Intracranial Electrophysiology Research.
Neurosurgery
Low-frequency cortical activity is a neuromodulatory target that tracks recovery after stroke.
Nature medicine
The genetic landscape of ganglioglioma.
Acta neuropathologica communications
Safety and outcomes of resection of butterfly glioblastoma.
Neurosurgical focus
A Spatial Map of Onset and Sustained Responses to Speech in the Human Superior Temporal Gyrus.
Current biology : CB
Direct cortical stimulation of inferior frontal cortex disrupts both speech and music production in highly trained musicians.
Cognitive neuropsychology
Multiple Subpial Transections for Medically Refractory Epilepsy: A Disaggregated Review of Patient-Level Data.
Neurosurgery
Seizure localization by chronic ambulatory electrocorticography.
Clinical neurophysiology practice
Direct electrical stimulation of human cortex evokes high gamma activity that predicts conscious somatosensory perception.
Journal of neural engineering
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain.
Frontiers in computational neuroscience
Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy.
Epilepsy & behavior case reports
Mirroring in the Human Brain: Deciphering the Spatial-Temporal Patterns of the Human Mirror Neuron System.
Cerebral cortex (New York, N.Y. : 1991)
Human Sensorimotor Cortex Control of Directly Measured Vocal Tract Movements during Vowel Production.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Neural correlates of sine-wave speech intelligibility in human frontal and temporal cortex.
Brain and language
Real-time classification of auditory sentences using evoked cortical activity in humans.
Journal of neural engineering
Multi-day rhythms modulate seizure risk in epilepsy.
Nature communications
Reductions in brain pericytes are associated with arteriovenous malformation vascular instability.
Journal of neurosurgery
Persistent neuronal activity in human prefrontal cortex links perception and action.
Nature human behaviour
Selective Interference with Syntactic Encoding during Sentence Production by Direct Electrocortical Stimulation of the Inferior Frontal Gyrus.
Journal of cognitive neuroscience
Semi-automated Anatomical Labeling and Inter-subject Warping of High-Density Intracranial Recording Electrodes in Electrocorticography.
Frontiers in neuroinformatics
Psychogenic nonepileptic seizures in patients with surgically treated temporal lobe epilepsy: Presurgical and de novo postsurgical occurrence.
Epilepsy & behavior : E&B
Intonational speech prosody encoding in the human auditory cortex.
Science (New York, N.Y.)
Dynamic tracking of non-stationarity in human ECoG activity.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
Sparse coding of ECoG signals identifies interpretable components for speech control in human sensorimotor cortex.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
Multi-scale visual analysis of time-varying electrocorticography data via clustering of brain regions.
BMC bioinformatics
Immediate Mood Scaler: Tracking Symptoms of Depression and Anxiety Using a Novel Mobile Mood Scale.
JMIR mHealth and uHealth
Prospective comparison of long-term pain relief rates after first-time microvascular decompression and stereotactic radiosurgery for trigeminal neuralgia.
Journal of neurosurgery
Perceptual restoration of masked speech in human cortex.
Nature communications
Systemic inaccuracies in the National Surgical Quality Improvement Program database: Implications for accuracy and validity for neurosurgery outcomes research.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
New Developments in Understanding the Complexity of Human Speech Production.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Methods for Specifying Scientific Data Standards and Modeling Relationships with Applications to Neuroscience.
Frontiers in neuroinformatics
Muscle synergies after stroke are correlated with perilesional high gamma.
Annals of clinical and translational neurology
Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.
Cancer discovery
Rates and Predictors of Seizure Freedom With Vagus Nerve Stimulation for Intractable Epilepsy.
Neurosurgery
Spatial resolution dependence on spectral frequency in human speech cortex electrocorticography.
Journal of neural engineering
Neural speech recognition: continuous phoneme decoding using spatiotemporal representations of human cortical activity.
Journal of neural engineering
Decoding speech using the timing of neural signal modulation.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
ECoG data analyses to inform closed-loop BCI experiments for speech-based prosthetic applications.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
Thin-film, high-density micro-electrocorticographic decoding of a human cortical gyrus.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
The peri-Sylvian cortical network underlying single word repetition revealed by electrocortical stimulation and direct neural recordings.
Brain and language
Dynamic Structure of Neural Variability in the Cortical Representation of Speech Sounds.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Seizure outcomes in nonresective epilepsy surgery: an update.
Neurosurgical review
Rate and complications of adult epilepsy surgery in North America: Analysis of multiple databases.
Epilepsy research
Stereotactic probability and variability of speech arrest and anomia sites during stimulation mapping of the language dominant hemisphere.
Journal of neurosurgery
New tools for studying microglia in the mouse and human CNS.
Proceedings of the National Academy of Sciences of the United States of America
Frontal and motor cortex contributions to response inhibition: evidence from electrocorticography.
Journal of neurophysiology
Human Superior Temporal Gyrus Organization of Spectrotemporal Modulation Tuning Derived from Speech Stimuli.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Major and minor complications in extraoperative electrocorticography: A review of a national database.
Epilepsy research
The sensitivity and significance of lateralized interictal slow activity on magnetoencephalography in focal epilepsy.
Epilepsy research
Epilepsy and brain tumors.
Handbook of clinical neurology
Minimally Invasive Epilepsy Surgery.
Neurosurgery clinics of North America
Epilepsy with temporal encephalocele: Characteristics of electrocorticography and surgical outcome.
Epilepsia
Seizures in supratentorial meningioma: a systematic review and meta-analysis.
Journal of neurosurgery
Stereotactic Laser Ablation for Hypothalamic Hamartoma.
Neurosurgery clinics of North America
Awake brain tumor resection during pregnancy: Decision making and technical nuances.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Two cases of rheumatoid meningitis.
Neuropathology : official journal of the Japanese Society of Neuropathology
Strategies for optical control and simultaneous electrical readout of extended cortical circuits.
Journal of neuroscience methods
Corpus callosotomy versus vagus nerve stimulation for atonic seizures and drop attacks: A systematic review.
Epilepsy & behavior : E&B
Oscillatory dynamics coordinating human frontal networks in support of goal maintenance.
Nature neuroscience
Transient aphasias after left hemisphere resective surgery.
Journal of neurosurgery
The influence of lexical statistics on temporal lobe cortical dynamics during spoken word listening.
Brain and language
Minimally invasive surgical approaches for temporal lobe epilepsy.
Epilepsy & behavior : E&B
Global and regional functional connectivity maps of neural oscillations in focal epilepsy.
Brain : a journal of neurology
A probabilistic map of the human ventral sensorimotor cortex using electrical stimulation.
Journal of neurosurgery
The cortical computations underlying feedback control in vocal production.
Current opinion in neurobiology
Dynamic encoding of speech sequence probability in human temporal cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Awake craniotomy in a patient with ejection fraction of 10%: considerations of cerebrovascular and cardiovascular physiology.
Journal of clinical anesthesia
National trends and complication rates for invasive extraoperative electrocorticography in the USA.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
The results of a third Gamma Knife procedure for recurrent trigeminal neuralgia.
Journal of neurosurgery
A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Contemporary model of language organization: an overview for neurosurgeons.
Journal of neurosurgery
Unilateral holohemispheric central nervous system lesions associated with medically refractory epilepsy in the pediatric population: a retrospective series of hemimegalencephaly and Rasmussen's encephalitis.
Journal of neurosurgery. Pediatrics
Control of spoken vowel acoustics and the influence of phonetic context in human speech sensorimotor cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Epilepsy surgery failure in children: a quantitative and qualitative analysis.
Journal of neurosurgery. Pediatrics
Initial experience with electronic tracking of specific tumor sites in men undergoing active surveillance of prostate cancer.
Urologic oncology
Isolated intracerebral light chain deposition disease: novel imaging and pathologic findings.
Clinical imaging
Dynamic speech representations in the human temporal lobe.
Trends in cognitive sciences
Rates and predictors of seizure freedom in resective epilepsy surgery: an update.
Neurosurgical review
Phonetic feature encoding in human superior temporal gyrus.
Science (New York, N.Y.)
Neural decoding of spoken vowels from human sensory-motor cortex with high-density electrocorticography.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
Seizure types and frequency in patients who "fail" temporal lobectomy for intractable epilepsy.
Neurosurgery
Safety and efficacy of motor mapping utilizing short pulse train direct cortical stimulation.
Stereotactic and functional neurosurgery
Hidden Markov model and support vector machine based decoding of finger movements using electrocorticography.
Journal of neural engineering
Speech map in the human ventral sensory-motor cortex.
Current opinion in neurobiology
Syllabic (~2-5 Hz) and fluctuation (~1-10 Hz) ranges in speech and auditory processing.
Hearing research
Managing common complex symptomatic epilepsies: tumors and trauma: american epilepsy society - 2012 annual course summary.
Epilepsy currents
Trends in surgical treatment for trigeminal neuralgia in the United States of America from 1988 to 2008.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas.
Neurosurgery
Seizure outcomes after resective surgery for extra-temporal lobe epilepsy in pediatric patients.
Journal of neurosurgery. Pediatrics
Seizure outcomes after temporal lobectomy in pediatric patients.
Journal of neurosurgery. Pediatrics
Emergent categorical representation of natural, complex sounds resulting from the early post-natal sound environment.
Neuroscience
Effects of temporal lobectomy on consciousness-impairing and consciousness-sparing seizures in children.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Neurosurgery and the dawning age of Brain-Machine Interfaces.
Surgical neurology international
Value of targeted prostate biopsy using magnetic resonance-ultrasound fusion in men with prior negative biopsy and elevated prostate-specific antigen.
European urology
Human cortical sensorimotor network underlying feedback control of vocal pitch.
Proceedings of the National Academy of Sciences of the United States of America
Transmantle sign in focal cortical dysplasia: a unique radiological entity with excellent prognosis for seizure control.
Journal of neurosurgery
Proceedings of the Third International Workshop on Advances in Electrocorticography.
Epilepsy & behavior : E&B
Relationship between hospital surgical volume, lobectomy rates, and adverse perioperative events at US epilepsy centers.
Journal of neurosurgery
Efficacy of vagus nerve stimulation in posttraumatic versus nontraumatic epilepsy.
Journal of neurosurgery
Real-time, time-frequency mapping of event-related cortical activation.
Journal of neural engineering
Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Characteristics and treatment of seizures in patients with high-grade glioma: a review.
Neurosurgery clinics of North America
Extent of surgical resection predicts seizure freedom in low-grade temporal lobe brain tumors.
Neurosurgery
Comparison of seizure control outcomes and the safety of vagus nerve, thalamic deep brain, and responsive neurostimulation: evidence from randomized controlled trials.
Neurosurgical focus
A meta-analysis of predictors of seizure freedom in the surgical management of focal cortical dysplasia.
Journal of neurosurgery
Rates and predictors of long-term seizure freedom after frontal lobe epilepsy surgery: a systematic review and meta-analysis.
Journal of neurosurgery
Reconstructing speech from human auditory cortex.
PLoS biology
Efficacy of vagus nerve stimulation for epilepsy by patient age, epilepsy duration, and seizure type.
Neurosurgery clinics of North America
Epilepsy surgery: the emerging field of neuromodulation.
Neurosurgery clinics of North America
Excess mortality for patients with residual disease following resection of pituitary adenomas.
Pituitary
Vagus nerve stimulation for epilepsy: a meta-analysis of efficacy and predictors of response.
Journal of neurosurgery
Predictors of seizure freedom in the surgical treatment of supratentorial cavernous malformations.
Journal of neurosurgery
Predictors of seizure freedom after surgery for malformations of cortical development.
Annals of neurology
Predictors of seizure freedom after resection of supratentorial low-grade gliomas. A review.
Journal of neurosurgery
Lead cap localization using ultrasound in deep brain stimulation surgery: technical note.
Minimally invasive neurosurgery : MIN
Incidence and management of venous air embolisms during awake deep brain stimulation surgery in a large clinical series.
Stereotactic and functional neurosurgery
Homotopic organization of essential language sites in right and bilateral cerebral hemispheric dominance.
Journal of neurosurgery
Single-trial speech suppression of auditory cortex activity in humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Early surgical intervention in adult patients with ganglioglioma is associated with improved clinical seizure outcomes.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Sub-centimeter language organization in the human temporal lobe.
Brain and language
Assessment of morbidity following resection of cingulate gyrus gliomas. Clinical article.
Journal of neurosurgery
Categorical speech representation in human superior temporal gyrus.
Nature neuroscience
Functional mapping-guided resection of low-grade gliomas in eloquent areas of the brain: improvement of long-term survival. Clinical article.
Journal of neurosurgery
Supratentorial cavernous malformations in eloquent and deep locations: surgical approaches and outcomes. Clinical article.
Journal of neurosurgery
Postoperative seizures following the resection of convexity meningiomas: are prophylactic anticonvulsants indicated? Clinical article.
Journal of neurosurgery
Long-term benefit sustained after bilateral pallidal deep brain stimulation in patients with refractory tardive dystonia.
Stereotactic and functional neurosurgery
Cortical spatio-temporal dynamics underlying phonological target detection in humans.
Journal of cognitive neuroscience
Nonresective epilepsy surgery.
Epilepsia
Seizure control outcomes after resection of dysembryoplastic neuroepithelial tumor in 50 patients.
Journal of neurosurgery. Pediatrics
Magnetic source imaging for the surgical evaluation of electroencephalography-confirmed secondary bilateral synchrony in intractable epilepsy.
Journal of neurosurgery
Cortical representation of ipsilateral arm movements in monkey and man.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Multiinstitutional validation of the University of California at San Francisco Low-Grade Glioma Prognostic Scoring System. Clinical article.
Journal of neurosurgery
Seizure characteristics and control after microsurgical resection of supratentorial cerebral cavernous malformations.
Neurosurgery
Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study.
Journal of neuro-oncology
Preoperative prognostic classification system for hemispheric low-grade gliomas in adults.
Journal of neurosurgery
Long-term recurrence and mortality after surgery and adjuvant radiotherapy for nonfunctional pituitary adenomas.
Journal of neurosurgery
Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Seizure characteristics and control following resection in 332 patients with low-grade gliomas.
Journal of neurosurgery
Neuronal responses to passive movement in the globus pallidus internus in primary dystonia.
Journal of neurophysiology
Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury period.
Neurosurgery
The role of early follow-up computed tomography imaging in the management of traumatic brain injury patients with intracranial hemorrhage.
The Journal of trauma
Critical period window for spectral tuning defined in the primary auditory cortex (A1) in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma.
Journal of neurosurgery
Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury period.
Neurosurgery
The extended retrosigmoid approach: an alternative to radical cranial base approaches for posterior fossa lesions.
Neurosurgery
Focal cortical dysplasia: a review of pathological features, genetics, and surgical outcome.
Neurosurgical focus
Development of spectral and temporal response selectivity in the auditory cortex.
Proceedings of the National Academy of Sciences of the United States of America
Thrombotic intracranial aneurysms: classification scheme and management strategies in 68 patients.
Neurosurgery
Temporal plasticity in the primary auditory cortex induced by operant perceptual learning.
Nature neuroscience
Renal cell carcinoma metastatic to the choroid mimicking intraventricular meningioma.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Progressive degradation and subsequent refinement of acoustic representations in the adult auditory cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Falcotentorial meningiomas: clinical, neuroimaging, and surgical features in six patients.
Neurosurgical focus
Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Environmental noise retards auditory cortical development.
Science (New York, N.Y.)