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Chelsea Bahney, PhD
My long-term research goal is to develop translationally relevant therapies or diagnostics that improve health. Specifically, my academic research lab focuses on the central process of endochondral ossification, which is the mechanism of indirect bone formation by which cartilage transforms into bone during embryonic development, postnatal growth, fracture healing, and osteoarthritis. My research efforts into the fate of chondrocytes during endochondral fracture repair have contributed to a significant paradigm shift in the field’s understanding of how chondrocytes directly contribute to bone regeneration.
More recently I have also developed robust funding to investigate the role that crosstalk with the nervous system plays in tissue regeneration. Within the orthopaedic space, my lab is investigating how neuropeptides contribute directly to bone healing and interact with pain signaling. I have also developed an NIH and CIRM funded partnership with Dr. Sarah Knox to look at how the nerve leads to salivary gland regeneration. Building from these mechanistic advancements, we are integrating novel bioactive material platforms to therapeutically stimulate tissue-nerve crosstalk.
