Chelsea Bahney, PhD

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Associate Adjunct Professor
Orthopaedic Surgery
+1 628 206-5362

My long-term research goal is to develop translationally relevant therapies or diagnostics that improve health. Specifically, my academic research lab focuses on the central process of endochondral ossification, which is the mechanism of indirect bone formation by which cartilage transforms into bone during embryonic development, postnatal growth, fracture healing, and osteoarthritis. My research efforts into the fate of chondrocytes during endochondral fracture repair have contributed to a significant paradigm shift in the field’s understanding of how chondrocytes directly contribute to bone regeneration.

More recently I have also developed robust funding to investigate the role that crosstalk with the nervous system plays in tissue regeneration. Within the orthopaedic space, my lab is investigating how neuropeptides contribute directly to bone healing and interact with pain signaling. I have also developed an NIH and CIRM funded partnership with Dr. Sarah Knox to look at how the nerve leads to salivary gland regeneration. Building from these mechanistic advancements, we are integrating novel bioactive material platforms to therapeutically stimulate tissue-nerve crosstalk.

Publications

Cellular biology of fracture healing.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Bahney CS, Zondervan RL, Allison P, Theologis A, Ashley JW, Ahn J, Miclau T, Marcucio RS, Hankenson KD

Review Article

The multifaceted role of the vasculature in endochondral fracture repair

Bahney, CS; Hu, DP; Miclau, T; Marcucio, RS

Impedance spectroscopy to monitor fracture healing.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Lin MC, Herfat ST, Bahney CS, Marmor M, Maharbiz MM

Contributor contact details.

Bone Substitute Biomaterials

K.K. Mallick, S. Sprio, M. Sandri, M. Iafisco, A. Ruffini, S. Minardi, A. Tampieri, P. Bhattacharya, G.H. van Lenthe, E.B. Hunziker, T.J. Blokhuis, V. Guarino, M.G. Raucci, A. Ronca, V. Cirillo, L. Ambrosio, K.K. Mallick, J. Winnett, A. Bansiddhi, D.C. Dunand, G.C. Wang, Z.F. Lu, H. Zreiqat, C.S. Bahney, R.S. Marcucio, J. Venkatesan, S.K. Kim, L. Grøndahl, C.S. Goonasekera, K.S. Jack, S.A. Clarke, P. Walsh

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