The Journal of clinical investigation

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Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.

The Journal of clinical investigation

Winkler J, Tan W, Diadhiou CM, McGinnis CS, Abbasi A, Hasnain S, Durney S, Atamaniuc E, Superville D, Awni L, Lee JV, Hinrichs JH, Wagner PS, Singh N, Hein MY, Borja M, Detweiler AM, Liu SY, Nanjaraj A, Sitarama V, Rugo HS, Neff N, Gartner ZJ, Oliveira Pisco A, Goga A, Darmanis S, Werb Z

Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis.

The Journal of clinical investigation

Reyes EA, Castillo-Azofeifa D, Rispal J, Wald T, Zwick RK, Palikuqi B, Mujukian A, Rabizadeh S, Gupta AR, Gardner JM, Boffelli D, Gartner ZJ, Klein OD

Leveraging microenvironmental synthetic lethalities to treat cancer.

The Journal of clinical investigation

Metcalf KJ, Alazzeh A, Werb Z, Weaver VM

Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix.

The Journal of clinical investigation

Jiang H, Torphy RJ, Steiger K, Hongo H, Ritchie AJ, Kriegsmann M, Horst D, Umetsu SE, Joseph NM, McGregor K, Pishvaian MJ, Blais EM, Lu B, Li M, Hollingsworth M, Stashko C, Volmar K, Yeh JJ, Weaver VM, Wang ZJ, Tempero MA, Weichert W, Collisson EA

Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.

The Journal of clinical investigation

Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM

Pro-resolving lipid mediators in vascular disease.

The Journal of clinical investigation

Conte MS, Desai TA, Wu B, Schaller M, Werlin E

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

The Journal of clinical investigation

Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM

Sympathetic and baroreceptor reflex function in neurally mediated syncope evoked by tilt.

The Journal of clinical investigation

Mosqueda-Garcia R, Furlan R, Fernandez-Violante R, Desai T, Snell M, Jarai Z, Ananthram V, Robertson RM, Robertson D

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