Jeremy Gordon, PhD

Assoc Professor In Residence

Radiology

+1 415 476-9786

Dr. Jeremy Gordon, PhD, is an Associate Professor in the Department of Radiology & Biomedical Imaging. He received his BS in Physics & Astronomy from the University of Georgia in 2008 and his PhD in Medical Physics from the University of Wisconsin-Madison in 2013. He has been
at UCSF since 2013, first as a postdoctoral scholar working with Dr. Peder Larson (2013 - 2016) and then as a Senior Bioengineer (2016 - 2020) before joining the faculty in 2020.

His research is focused on developing novel techniques to acquire and analyze metabolic information, leveraging a team science approach to advance the research and clinical care of patients utilizing hyperpolarized 13C and other x-nuclei such as 2H for a wide range of diseases. These methods are currently being applied in patients with pancreatic cancer as a novel tool to predict treatment response using hyperpolarized metabolic imaging, to characterize metabolic changes associated with multiple sclerosis using hyperpolarized metabolic imaging, and to develop new methods of measuring glucose metabolism in vivo and its impairment in Alzheimer’s Disease using deuterium metabolic imaging.

Publications:

Consensus Recommendations for Hyperpolarized [1-13C]pyruvate MRI Multi-center Human Studies.

arxiv

Punwani S, Larson PE, Laustsen C, VanderMeulen J, Ardenkjær-Larsen JH, Autry AW, Bankson JA, Bernard J, Bok R, Bertelsen LB, Che J, Chen AP, Chowdhury R, Comment A, Cunningham CH, Dang D, Gallagher FA, Gaunt A, Gong Y, Gordon JW, Grimmer A, Grist J, Hansen ESS, Lerche MH, Hesketh RL, Hoevener JB, Hsieh CY, Keshari KR, Kozerke S, Lanz T, Mayer D, McLean M, Park JM, Slater J, Tyler D, Vanderheyden JL, von Morze C, Zaccagna F, Zaha V, Xu D, Vigneron D, HP 13C MRI Consensus Group

Open-source implementation of X-nuclear sequences using the Pulseq framework.

Magnetic resonance in medicine

Liu X, Cui D, Larson PEZ, Mayer D, Korzowski A, Nielsen JF, Schulte RF, Mu C, Carvajal L, Xu D, Gordon JW, Vigneron DB, Flavell RR, Wang ZJ

Translation of hyperpolarized [13C,15N2]urea MRI for novel human brain perfusion studies.

Npj imaging

Kim Y, Chen HY, Nickles T, Shkliar I, Dang D, Slater J, Wang C, Gordon JW, Tan CT, Suszczynski C, Maddali S, Gaunt A, Chen R, Villanueva-Meyer J, Xu D, Larson PEZ, Kurhanewicz J, Bok RA, Chang S, Vigneron DB

Clinical Translation of Hyperpolarized 13C Metabolic Probes for Glioma Imaging.

AJNR. American journal of neuroradiology

Autry AW, Kim Y, Dang D, Chen HY, Slater JB, Bok RA, Xu D, Lupo JM, Gordon JW, Larson PEZ, Vigneron DB, Li Y, Chang SM

A data-driven approach for improved quantification of in vivo metabolic conversion rates of hyperpolarized [1-13C]pyruvate.

Magnetic resonance in medicine

Kim Y, Nickles TM, Lee PM, Bok RA, Gordon JW, Larson PEZ, Vigneron DB, von Morze C, Ohliger MA

Deuterium Metabolic Imaging of the Brain Using 2-Deoxy-2-[2H2]-d-glucose: A Non-ionizing [18F]FDG Alternative.

JACS Au

Gao X, Qiao K, Wilson DM, Chaumeil MM, Gordon JW

Dual hyperpolarized [1-13C]pyruvate and [13C]urea magnetic resonance imaging of prostate cancer.

Journal of Magnetic Resonance Open

Ivan de Kouchkovsky, Hao Nguyen, Hsin-Yu Chen, Xiaoxi Liu, Hecong Qin, Bradley A. Stohr, Romelyn Delos Santos, Michael A. Ohliger, Zhen Jane Wang, Robert A. Bok, Jeremy W. Gordon, Peder E.Z. Larson, Mary Frost, Kimberly Okamoto, Daniel Gebrezgiabhier, Matthew Cooperberg, Daniel B. Vigneron, John Kurhanewicz, Rahul Aggarwal

Accelerated parallel magnetic resonance imaging with compressed sensing using structured sparsity.

Journal of medical imaging (Bellingham, Wash.)

Dwork N, Gordon JW, Englund EK

Correlating survival outcomes in patients with advanced prostate cancer with novel hyperpolarized 13 C MRI metabolic imaging biomarkers.

Journal of Clinical Oncology

Hsin-Yu Chen, Ivan de Kouchkovsky, Robert A. Bok, Michael A. Ohliger, Zhen J. Wang, Daniel Gebrezgiabhier, Tanner Nickles, Lucas E. Carvajal, Jeremy W. Gordon, Peder E.Z. Larson, John Kurhanewicz, Rahul Raj Aggarwal, Daniel B. Vigneron

Data Format Standardization and DICOM Integration for Hyperpolarized 13C MRI.

arxiv

Diaz E, Sriram R, Gordon JW, Sinha A, Liu X, Sahin S, Crane J, Olson MP, Chen HY, Bernard J, Vigneron DB, Wang ZJ, Xu D, Larson PEZ

Data Format Standardization and DICOM Integration for Hyperpolarized 13C MRI.

Journal of imaging informatics in medicine

Diaz E, Sriram R, Gordon JW, Sinha A, Liu X, Sahin SI, Crane JC, Olson MP, Chen HY, Bernard JML, Vigneron DB, Wang ZJ, Xu D, Larson PEZ

Current methods for hyperpolarized [1-13 C]pyruvate MRI human studies.

Magnetic resonance in medicine

Larson PEZ, Bernard JML, Bankson JA, Bøgh N, Bok RA, Chen AP, Cunningham CH, Gordon JW, Hövener JB, Laustsen C, Mayer D, McLean MA, Schilling F, Slater JB, Vanderheyden JL, von Morze C, Vigneron DB, Xu D, HP 13C MRI Consensus Group

Advanced Hyperpolarized 13C Metabolic Imaging Protocol for Patients with Gliomas: A Comprehensive Multimodal MRI Approach.

Cancers

Autry AW, Vaziri S, Gordon JW, Chen HY, Kim Y, Dang D, LaFontaine M, Noeske R, Bok R, Villanueva-Meyer JE, Clarke JL, Oberheim Bush NA, Chang SM, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Li Y

Hyperpolarized 13 C metabolic imaging of the human abdomen with spatiotemporal denoising.

Magnetic resonance in medicine

Nickles TM, Kim Y, Lee PM, Chen HY, Ohliger M, Bok RA, Wang ZJ, Larson PEZ, Vigneron DB, Gordon JW

Kiosk 7R-TB-07 Quantification of Abnormal Metabolism in Hypertrophic Cardiomyopathy Patients Using Hyperpolarized [1-13c]-pyruvate MRI.

Journal of Cardiovascular Magnetic Resonance

Avantika Sinha, Xiaoxi Liu, Shuyu Tang, Nicholas Dwork, Sanjay Sivalokanathan, Jing Liu, Robert Bok, Karen Ordovas, James Slater, Jeremy Gordon, Roselle Abraham, Peder Larson

Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate CMR evaluated in an oral glucose challenge.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

Larson PEZ, Tang S, Liu X, Sinha A, Dwork N, Sivalokanathan S, Liu J, Bok R, Ordovas KG, Slater J, Gordon JW, Abraham MR

Probing human heart TCA cycle metabolism and response to glucose load using hyperpolarized [2-13 C]pyruvate MRS.

NMR in biomedicine

Chen HY, Gordon JW, Dwork N, Chung BT, Riselli A, Sivalokanathan S, Bok RA, Slater JB, Vigneron DB, Abraham MR, Larson PEZ

Hyperpolarized 13 C Metabolic MRI of Patients with Pancreatic Ductal Adenocarcinoma.

Journal of magnetic resonance imaging : JMRI

Gordon JW, Chen HY, Nickles T, Lee PM, Bok R, Ohliger MA, Okamoto K, Ko AH, Larson PEZ, Wang ZJ

Dynamic T2* relaxometry of hyperpolarized [1-13 C]pyruvate MRI in the human brain and kidneys.

Magnetic resonance in medicine

Liu X, Cui D, Xu D, Bok R, Wang ZJ, Vigneron DB, Larson PEZ, Gordon JW

Clinically Translatable Hyperpolarized 13C Bicarbonate pH Imaging Method for Use in Prostate Cancer.

ACS sensors

Mu C, Liu X, Kim Y, Riselli A, Korenchan DE, Bok RA, Delos Santos R, Sriram R, Qin H, Nguyen H, Gordon JW, Slater J, Larson PEZ, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR

Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-13C]Pyruvate MR Spectroscopy.

medRxiv : the preprint server for health sciences

Chen HY, Gordon JW, Dwork N, Chung BT, Riselli A, Sivalokanathan S, Bok RA, Slater JB, Vigneron DB, Abraham MR, Larson PEZ

Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate MRI evaluated in an oral glucose challenge.

medRxiv : the preprint server for health sciences

Larson PEZ, Tang S, Liu X, Sinha A, Dwork N, Sivalokanathan S, Liu J, Bok R, Ordovas KG, Slater J, Gordon JW, Abraham MR

Investigating cerebral perfusion with high resolution hyperpolarized [1-13 C]pyruvate MRI.

Magnetic resonance in medicine

Hu JY, Vaziri S, Bøgh N, Kim Y, Autry AW, Bok RA, Li Y, Laustsen C, Xu D, Larson PEZ, Chang S, Vigneron DB, Gordon JW

Hyperpolarized [2-13C]Pyruvate MR Molecular Imaging with Whole Brain Coverage.

NeuroImage

Chung BT, Kim Y, Gordon JW, Chen HY, Autry AW, Lee PM, Hu JY, Tan CT, Suszczynski C, Chang SM, Villaneuva-Meyer JE, Bok RA, Larson PEZ, Xu D, Li Y, Vigneron DB

Multi-parametric hyperpolarized 13C/1H imaging reveals Warburg-related metabolic dysfunction and associated regional heterogeneity in high-grade human gliomas.

NeuroImage. Clinical

Autry AW, Vaziri S, LaFontaine M, Gordon JW, Chen HY, Kim Y, Villanueva-Meyer JE, Molinaro A, Clarke JL, Oberheim Bush NA, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Chang SM, Li Y

A user independent denoising method for x-nuclei MRI and MRS.

Magnetic resonance in medicine

Christensen NV, Vaeggemose M, Bøgh N, Hansen ESS, Olesen JL, Kim Y, Vigneron DB, Gordon JW, Jespersen SN, Laustsen C

Sodium in the Skin: A summary of the physiology and scoping review of disease associations.

Clinical and experimental dermatology

Chattopadhyay A, Tully J, Shan J, Sheikh S, Ohliger M, Gordon J, Mauro T, Abuabara K

A metabolite specific 3D stack-of-spirals bSSFP sequence for improved bicarbonate imaging in hyperpolarized [1-13C]Pyruvate MRI.

Journal of magnetic resonance (San Diego, Calif. : 1997)

Liu X, Tang S, Cui D, Bok RA, Chen HY, Gordon JW, Wang ZJ, Larson PEZ

Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized 13C-Pyruvate MRI.

Tomography (Ann Arbor, Mich.)

Sahin SI, Ji X, Agarwal S, Sinha A, Mali I, Gordon JW, Mattingly M, Subramaniam S, Kurhanewicz J, Larson PEZ, Sriram R

Optimization in the space domain for density compensation with the nonuniform FFT.

Magnetic resonance imaging

Dwork N, O'Connor D, Johnson EMI, Baron CA, Gordon JW, Pauly JM, Larson PEZ

Model-constrained reconstruction accelerated with Fourier-based undersampling for hyperpolarized [1-13 C] pyruvate imaging.

Magnetic resonance in medicine

Xu Z, Michel KA, Walker CM, Harlan CJ, Martinez GV, Gordon JW, Chen HY, Vigneron DB, Bankson JA

TMET-04. DETECTING DYNAMIC PYRUVATE TUMOR METABOLISM IN PATIENTS WITH GLIOMA USING HYPERPOLARIZED CARBON-13 METABOLIC IMAGING.

Neuro-Oncology

Yan Li, Janine Lupo, Adam Autry, Sana Vaziri, Jeremy Gordon, Marisa Lafontaine, Chen Hsin-Yu, Yaewon Kim, Jasmine Hu, Wendy Ma, Javier Villanueva-Meyer, Peder Larson, Duan Xu, Nancy Ann Oberheim Bush, Jennifer Clarke, Daniel Vigneron, Susan M Chang

Assessment of higher-order singular value decomposition denoising methods on dynamic hyperpolarized [1-13C]pyruvate MRI data from patients with glioma.

NeuroImage. Clinical

Vaziri S, Autry AW, Lafontaine M, Kim Y, Gordon JW, Chen HY, Hu JY, Lupo JM, Chang SM, Clarke JL, Villanueva-Meyer JE, Bush NAO, Xu D, Larson PEZ, Vigneron DB, Li Y

Improving multiparametric MR-transrectal ultrasound guided fusion prostate biopsies with hyperpolarized 13 C pyruvate metabolic imaging: A technical development study.

Magnetic resonance in medicine

Chen HY, Bok RA, Cooperberg MR, Nguyen HG, Shinohara K, Westphalen AC, Wang ZJ, Ohliger MA, Gebrezgiabhier D, Carvajal L, Gordon JW, Larson PEZ, Aggarwal R, Kurhanewicz J, Vigneron DB

Kinetic analysis of multi-resolution hyperpolarized 13 C human brain MRI to study cerebral metabolism.

Magnetic resonance in medicine

Hu JY, Kim Y, Autry AW, Frost MM, Bok RA, Villanueva-Meyer JE, Xu D, Li Y, Larson PEZ, Vigneron DB, Gordon JW

Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [13 C,15 N2 ]urea + [1-13 C]pyruvate simultaneous perfusion and metabolic imaging.

Magnetic resonance in medicine

Liu X, Tang S, Mu C, Qin H, Cui D, Lai YC, Riselli AM, Delos Santos R, Carvajal L, Gebrezgiabhier D, Bok RA, Chen HY, Flavell RR, Gordon JW, Vigneron DB, Kurhanewicz J, Larson PEZ

Whole-Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [1-13 C]pyruvate MRI.

Journal of magnetic resonance imaging : JMRI

Lee PM, Chen HY, Gordon JW, Wang ZJ, Bok R, Hashoian R, Kim Y, Liu X, Nickles T, Cheung K, Alas FL, Daniel H, Larson PEZ, von Morze C, Vigneron DB, Ohliger MA

Initial Experience on Hyperpolarized [1-13C]Pyruvate MRI Multicenter Reproducibility-Are Multicenter Trials Feasible?

Tomography (Ann Arbor, Mich.)

Bøgh N, Gordon JW, Hansen ESS, Bok RA, Blicher JU, Hu JY, Larson PEZ, Vigneron DB, Laustsen C

Instrumentation for Hydrogenative Parahydrogen-Based Hyperpolarization Techniques.

Analytical chemistry

Schmidt AB, Bowers CR, Buckenmaier K, Chekmenev EY, de Maissin H, Eills J, Ellermann F, Glöggler S, Gordon JW, Knecht S, Koptyug IV, Kuhn J, Pravdivtsev AN, Reineri F, Theis T, Them K, Hövener JB

NIMG-21. VARIABLE RESOLUTION HYPERPOLARIZED [2-13C]PYRUVATE MRI IN HEALTHY VOLUNTEERS AND PATIENTS WITH IDH-MUTANT GLIOMA.

Neuro-Oncology

Sana Vaziri, Yaewon Kim, Adam Autry, Hsin-Yu Chen, Jeremy Gordon, Marisa LaFontaine, Jasmine Hu, Janine Lupo, Jennifer Clarke, Javier Villanueva-Meyer, Nancy Ann Oberheim-Bush, Susan Chang, Duan Xu, Peder Larson, Daniel Vigneron, Yan Li

NIMG-43. ADVANCED MULTI-PARAMETRIC HYPERPOLARIZED 13C/1H IMAGING OF GBM.

Neuro-Oncology

Adam Autry, Sana Vaziri, Marisa LaFontaine, Jeremy Gordon, Hsin-Yu Chen, Javier Villanueva-Meyer, Susan Chang, Jennifer Clarke, Duan Xu, Janine Lupo, Peder Larson, Daniel Vigneron, Yan Li

Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Immune Checkpoint Inhibitor Therapy in Prostate Cancer.

European urology

de Kouchkovsky I, Chen HY, Ohliger MA, Wang ZJ, Bok RA, Gordon JW, Larson PEZ, Frost M, Okamoto K, Cooperberg MR, Kurhanewicz J, Vigneron DB, Aggarwal R

Deuterium Metabolic Imaging—Rediscovery of a Spectroscopic Tool.

Metabolites

Ilona Polvoy, Hecong Qin, Robert R. Flavell, Jeremy Gordon, Pavithra Viswanath, Renuka Sriram, Michael A. Ohliger, David M. Wilson

Clinical translation of hyperpolarized 13 C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging.

Magnetic resonance in medicine

Qin H, Tang S, Riselli AM, Bok RA, Delos Santos R, van Criekinge M, Gordon JW, Aggarwal R, Chen R, Goddard G, Zhang CT, Chen A, Reed G, Ruscitto DM, Slater J, Sriram R, Larson PEZ, Vigneron DB, Kurhanewicz J

Specialized computational methods for denoising, B1 correction, and kinetic modeling in hyperpolarized 13 C MR EPSI studies of liver tumors.

Magnetic resonance in medicine

Lee PM, Chen HY, Gordon JW, Zhu Z, Larson PEZ, Dwork N, Van Criekinge M, Carvajal L, Ohliger MA, Wang ZJ, Xu D, Kurhanewicz J, Bok RA, Aggarwal R, Munster PN, Vigneron DB

Denoising of hyperpolarized 13 C MR images of the human brain using patch-based higher-order singular value decomposition.

Magnetic resonance in medicine

Kim Y, Chen HY, Autry AW, Villanueva-Meyer J, Chang SM, Li Y, Larson PEZ, Brender JR, Krishna MC, Xu D, Vigneron DB, Gordon JW

Hyperpolarized Metabolic MRI-Acquisition, Reconstruction, and Analysis Methods.

Metabolites

Larson PEZ, Gordon JW

Metabolic MRI with hyperpolarized [1-13C]pyruvate separates benign oligemia from infarcting penumbra in porcine stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Bøgh N, Olin RB, Hansen ES, Gordon JW, Bech SK, Bertelsen LB, Sánchez-Heredia JD, Blicher JU, Østergaard L, Ardenkjær-Larsen JH, Bok RA, Vigneron DB, Laustsen C

Metabolic imaging with hyperpolarized 13 C pyruvate magnetic resonance imaging in patients with renal tumors-Initial experience.

Cancer

Tang S, Meng MV, Slater JB, Gordon JW, Vigneron DB, Stohr BA, Larson PEZ, Wang ZJ

Di-chromatic interpolation of magnetic resonance metabolic images.

Magma (New York, N.Y.)

Dwork N, Gordon JW, Tang S, O'Connor D, Hansen ESS, Laustsen C, Larson PEZ

3 HP acquisition methods: pulse sequences, reconstruction, and RF coils.

Jeremy W. Gordon, Jack J. Miller

NIMG-50. INITIAL EXPERIENCE: DETECTION OF ABERRANT HYPERPOLARIZED [1-13C]PYRUVATE METABOLISM IN PATIENTS WITH GBM PRIOR TO RESECTION.

Neuro-Oncology

Adam Autry, Jeremy Gordon, Marisa LaFontaine, Hsin-Yu Chen, Javier Villanueva-Meyer, Susan Chang, Jennifer Clarke, Duan Xu, Janine Lupo, Peder Larson, Daniel Vigneron, Yan Li

Slice profile effects on quantitative analysis of hyperpolarized pyruvate.

NMR in biomedicine

Walker CM, Gordon JW, Xu Z, Michel KA, Li L, Larson PEZ, Vigneron DB, Bankson JA

55 Mn-based fiducial markers for rapid and automated RF coil localization for hyperpolarized 13 C MRI.

Magnetic resonance in medicine

Ohliger MA, Gordon JW, Carvajal L, Larson PEZ, Ou JJ, Agarwal S, Zhu Z, Vigneron DB, von Morze C

A variable resolution approach for improved acquisition of hyperpolarized 13 C metabolic MRI.

Magnetic resonance in medicine

Gordon JW, Autry AW, Tang S, Graham JY, Bok RA, Zhu X, Villanueva-Meyer JE, Li Y, Ohilger MA, Abraham MR, Xu D, Vigneron DB, Larson PEZ

Characterization of serial hyperpolarized 13C metabolic imaging in patients with glioma.

NeuroImage. Clinical

Autry AW, Gordon JW, Chen HY, LaFontaine M, Bok R, Van Criekinge M, Slater JB, Carvajal L, Villanueva-Meyer JE, Chang SM, Clarke JL, Lupo JM, Xu D, Larson PEZ, Vigneron DB, Li Y

Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13 C MRSI.

Magnetic resonance in medicine

Chen HY, Autry AW, Brender JR, Kishimoto S, Krishna MC, Vareth M, Bok RA, Reed GD, Carvajal L, Gordon JW, van Criekinge M, Korenchan DE, Chen AP, Xu D, Li Y, Chang SM, Kurhanewicz J, Larson PEZ, Vigneron DB

Hyperpolarized 13 C MRI data acquisition and analysis in prostate and brain at University of California, San Francisco.

NMR in biomedicine

Crane JC, Gordon JW, Chen HY, Autry AW, Li Y, Olson MP, Kurhanewicz J, Vigneron DB, Larson PEZ, Xu D

Fast Imaging for Hyperpolarized MR Metabolic Imaging.

Journal of magnetic resonance imaging : JMRI

Gordon JW, Chen HY, Dwork N, Tang S, Larson PEZ

Simultaneous T1 and T2 mapping of hyperpolarized 13C compounds using the bSSFP sequence.

Journal of magnetic resonance (San Diego, Calif. : 1997)

Milshteyn E, Reed GD, Gordon JW, von Morze C, Cao P, Tang S, Leynes AP, Larson PEZ, Vigneron DB

CBMT-26. SERIAL CHARACTERIZATION OF HYPERPOLARIZED [1-13C]PYRUVATE METABOLISM IN PATIENTS WITH GLIOMA AND THE INFLUENCE OF BEVACIZUMAB.

Neuro-Oncology

Adam Autry, Jeremy Gordon, Hsin-Yu Chen, Marisa Lafontaine, Javier Villanueva-Meyer, Susan Chang, Duan Xu, Peder Larson, Daniel Vigneron, Yan Li

CBMT-36. INITIAL EXPERIENCE WITH HYPERPOLARIZED [2-13C]PYRUVATE MR IMAGING IN PATIENTS WITH IDH-MUTANT GLIOMA.

Neuro-Oncology

Adam Autry, Brian Chung, Hsin-Yu Chen, Jeremy Gordon, Marisa Lafontaine, Susan Chang, Javier Villanueva-Meyer, Peder Larson, Daniel Vigneron, Yan Li

NIMG-57. SERIAL HYPERPOLARIZED 13C PYRUVATE AND 1H METABOLIC IMAGING IN RECURRENT HIGH-GRADE GLIOMA.

Neuro-Oncology

Javier Villanueva-Meyer, Adam Autry, Jeremy Gordon, Hsin-Yu Chen, Marisa Lafontaine, Susan Chang, Duan Xu, Peder Larson, Daniel Vigneron, Yan Li

Hyperpolarized 13C-pyruvate MRI detects real-time metabolic flux in prostate cancer metastases to bone and liver: a clinical feasibility study.

Prostate cancer and prostatic diseases

Chen HY, Aggarwal R, Bok RA, Ohliger MA, Zhu Z, Lee P, Gordon JW, van Criekinge M, Carvajal L, Slater JB, Larson PEZ, Small EJ, Kurhanewicz J, Vigneron DB

Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging.

Magnetic resonance in medicine

Korenchan DE, Gordon JW, Subramaniam S, Sriram R, Baligand C, VanCriekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR

DIPG-31. FEASIBILITY OF HYPERPOLARIZED 13C METABOLIC IMAGING IN PEDIATRIC PATIENTS WITH DIPG AND OTHER CNS CANCERS.

Neuro-Oncology

Adam Autry, Ilwoo Park, Hsin-Yu Chen, Jeremy Gordon, Cassie Kline-Nunnally, Daniel Vigneron, Janine Lupo, Yan Li, Duan Xu, Sabine Mueller

Comparison between 8- and 32-channel phased-array receive coils for in vivo hyperpolarized 13 C imaging of the human brain.

Magnetic resonance in medicine

Autry AW, Gordon JW, Carvajal L, Mareyam A, Chen HY, Park I, Mammoli D, Vareth M, Chang SM, Wald LL, Xu D, Vigneron DB, Nelson SJ, Li Y

Hyperpolarized 13C MRI: State of the Art and Future Directions.

Radiology

Wang ZJ, Ohliger MA, Larson PEZ, Gordon JW, Bok RA, Slater J, Villanueva-Meyer JE, Hess CP, Kurhanewicz J, Vigneron DB

Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies.

Journal of magnetic resonance (San Diego, Calif. : 1997)

Zhu Z, Zhu X, Ohliger MA, Tang S, Cao P, Carvajal L, Autry AW, Li Y, Kurhanewicz J, Chang S, Aggarwal R, Munster P, Xu D, Larson PEZ, Vigneron DB, Gordon JW

Pulse sequence considerations for quantification of pyruvate-to-lactate conversion kPL in hyperpolarized 13 C imaging.

NMR in biomedicine

Chen HY, Gordon JW, Bok RA, Cao P, von Morze C, van Criekinge M, Milshteyn E, Carvajal L, Hurd RE, Kurhanewicz J, Vigneron DB, Larson PEZ

NIMG-08. REPRODUCIBILITY OF HYPERPOLARIZED C-13 METABOLIC IMAGING IN PATIENTS WITH GLIOMA.

Neuro-Oncology

Adam Autry, Jeremy Gordon, Marisa Lafontaine, Javier Villanueva-Meyer, Daniel Vigneron, Susan Chang, Sarah Nelson, Yan Li

NIMG-66. COMPARISON OF STEADY STATE AND DYNAMIC BRAIN METABOLISM BY USING 1H MRSI AND HYPERPOLARIZED [1-13C]PYRUVATE IMAGING IN PATIENTS WITH GLIOMA.

Neuro-Oncology

Yan Li, Adam Autry, Jeremy Gordon, Jason Crane, Beck Olson, Marisa Lafontaine, Ilwoo Park, Javier Villanueva-Meyer, Daniel Vigneron, Susan Chang, Sarah Nelson

Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.

Magnetic resonance in medicine

Gordon JW, Chen HY, Autry A, Park I, Van Criekinge M, Mammoli D, Milshteyn E, Bok R, Xu D, Li Y, Aggarwal R, Chang S, Slater JB, Ferrone M, Nelson S, Kurhanewicz J, Larson PEZ, Vigneron DB

Dynamic diffusion-weighted hyperpolarized 13 C imaging based on a slice-selective double spin echo sequence for measurements of cellular transport.

Magnetic resonance in medicine

Zhu X, Gordon JW, Bok RA, Kurhanewicz J, Larson PEZ

Investigation of analysis methods for hyperpolarized 13C-pyruvate metabolic MRI in prostate cancer patients.

NMR in biomedicine

Larson PEZ, Chen HY, Gordon JW, Korn N, Maidens J, Arcak M, Tang S, Criekinge M, Carvajal L, Mammoli D, Bok R, Aggarwal R, Ferrone M, Slater JB, Nelson SJ, Kurhanewicz J, Vigneron DB

High-resolution echo-planar spectroscopic imaging at ultra-high field.

NMR in biomedicine

Coello E, Noeske R, Burns BL, Gordon JW, Jakary A, Menze B, Haase A, Larson PEZ, Li Y, Schulte RF

Spatio-Temporally Constrained Reconstruction for Hyperpolarized Carbon-13 MRI Using Kinetic Models.

IEEE transactions on medical imaging

Maidens J, Gordon JW, Chen HY, Park I, Van Criekinge M, Milshteyn E, Bok R, Aggarwal R, Ferrone M, Slater JB, Kurhanewicz J, Vigneron DB, Arcak M, Larson PEZ

Hyperpolarized C-13 pyuvate metabolic MR imaging of solid tumor liver metastases as a biomarker of PI3K/mTOR pathway activity.

Journal of Clinical Oncology

Rahul Raj Aggarwal, Zihan Zhu, Michael Ohliger, Jeremy Gordon, Robert A. Bok, Jim Slater, John V. Kurhanewicz, Emily Boyd, Susan Calabrese, Christopher E. Sotto, Daniel B. Vigneron, Pamela N. Munster

Technique development of 3D dynamic CS-EPSI for hyperpolarized 13 C pyruvate MR molecular imaging of human prostate cancer.

Magnetic resonance in medicine

Chen HY, Larson PEZ, Gordon JW, Bok RA, Ferrone M, van Criekinge M, Carvajal L, Cao P, Pauly JM, Kerr AB, Park I, Slater JB, Nelson SJ, Munster PN, Aggarwal R, Kurhanewicz J, Vigneron DB

High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-13 C]pyruvate and [1-13 C]lactate with spectral suppression of alanine and pyruvate-hydrate.

Magnetic resonance in medicine

Milshteyn E, von Morze C, Gordon JW, Zhu Z, Larson PEZ, Vigneron DB

3D hyperpolarized C-13 EPI with calibrationless parallel imaging.

Journal of magnetic resonance (San Diego, Calif. : 1997)

Gordon JW, Hansen RB, Shin PJ, Feng Y, Vigneron DB, Larson PEZ

Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies.

Magnetic resonance in medicine

Park I, Larson PEZ, Gordon JW, Carvajal L, Chen HY, Bok R, Van Criekinge M, Ferrone M, Slater JB, Xu D, Kurhanewicz J, Vigneron DB, Chang S, Nelson SJ