The Need for Speed: Accelerating 3D Microscopy and Optical Imaging for Diverse Biomedical Applications.

Monthly Lecture Series from Bioengineering Leaders


Date of event: Tuesday, Feb. 8, 2022

Time: 12:00pm - 1:00pm

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Dr. Hillman received her undergraduate degree in Physics and PhD in Medical Physics and Bioengineering from University College London, London, UK. After a year at a medical devices start-up company in Boston, she completed post-doctoral work at Massachusetts General Hospital, Harvard Medical School before joining the faculty of Columbia University in 2006. She is currently a Herbert and Florence Irving Professor in the Zuckerman Mind Brain Behavior Institute at Columbia and a Professor of Biomedical Engineering and Radiology.

Dr. Hillman’s research to date has encompassed both the demonstration of new optical imaging and microscopy techniques, as well as studies of fundamental physiology, particularly related to real-time brain activity and the relationship between neuronal activity and blood flow in the living brain (neurovascular coupling). Her major technological contributions have included the development of dynamic contrast methods for small animal imaging (DyCE), development of ‘wide-field optical mapping’ (WFOM) techniques for imaging of neuronal activity and hemodynamics across the awake, behaving mouse brain, and development of swept, confocally-aligned planar excitation (SCAPE) imaging approaches for high-speed 3D microscopy. She has applied SCAPE microscopy to a wide range of collaborative biomedical studies, while also supporting its dissemination and adoption worldwide. Her recent technological developments include extensions of SCAPE for high-speed 3D imaging of cleared, whole human brains, and MediSCAPE, a system for rapid in-vivo, in-situ histopathology for clinical applications.


2022-01-25 00:00:00